This Issue at a Glance

Malhotra et al (p. 1438) retrospectively analyzed 203 673 patients from the Intelligent Research in Sight Registry® database to understand risk factors—including race, ethnicity, and insurance status—for poor baseline visual acuity (VA) diabetic retinopathy (DR) severity upon initiation of anti-VEGF therapy for macular edema (DME). Ethnicity, status were independently associated with worse VA DR severity, Hispanic Black those insured by Medicaid having treatment. ethnicity had strongest correlation ophthalmic health. The authors suggest need public health initiatives help improve ethnic insurance-based disparities disease DME Yu 1384) evaluated associations 12 systemic conditions previously reported as potential dry eye (DED) factors signs symptoms 535 moderate severe DED. Patients Sjögren syndrome (mean composite score 0.52 vs. 0.43 without disease), facial rosacea (0.47 0.43), rheumatoid arthritis 0.42), peripheral artery (0.50 daily smoking history (0.45 0.43) showed more than interest. There no significant DED thyroid dysfunction, osteoarthritis, diabetes, irritable bowel syndrome, hypercholesterolemia, hypertension, or hypertriglyceridemia, significantly Ocular Surface Disease Index. conclude that certain diseases signs. Soh 1393) conducted a systematic review meta-analysis 61 articles 55 population-based studies evaluate global extent undetected glaucoma. included 189 359 participants, whom 6949 manifest glaucoma, 5558 undetected. Globally, at least half all glaucoma cases estimated be every region, 43.78 million projected 2020 76.7% them being Africa Asia. (odds ratio [OR]:12.70) Asia (OR:3.41) higher odds compared Europe. Countries low Human Development Index (HDI; < 0.55) proportion countries medium very high HDI (≥ 0.55). researchers is highly prevalent across diverse communities worldwide, most commonly African Asian regions HDI. Phu 1405) performed head-to-head comparison 24-2C 10-2 test grids detecting central field defects 131 57 suspect patients. Global indices performance, such mean deviation, pattern standard sensitivity, similar. detected clusters 2+ contiguous points deficit 24-2C. also greater concordance structural functional deficits when structure-function comparisons locations where OCT colocalized. Test duration was longer (median 201.0 seconds) 154.0 seconds). similar performance proportionally amounts loss, but grid returned rate concordance. Kamalipour 1426) characterized artifacts seen angiography (OCTA) images healthy eyes. Analysis 5263 OCTA 63 subjects, suspects, 244 revealed 33.9% quality. majority (76.6%) acceptable image quality (QS) artifacts, 13.6% one artifact 9.8% two artifacts. Older age, male gender, absence tracking technology, scan area likelihood obtaining poor-quality images. under receiver operating characteristic curves QS signal strength index discriminating between good- 0.65 0.70, respectively. are frequent, their prevalence affected individual patient ocular conditions.